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American patients filling Valium prescriptions at pharmacies across the country may receive generic diazepam from various manufacturers, and all of these products have been determined by the FDA to be therapeutically equivalent to the brand-name medication. Valium Vietnam Over The Counter - Health Haven. Valium's half-life in healthy adults ranges from twenty to fifty hours for the parent compound, but its active metabolite desmethyldiazepam exhibits an even longer half-life of up to one hundred hours, producing effects that persist for days after a single dose and accumulate significantly with repeated administration. American physicians who prescribe Valium for conditions such as anxiety or muscle spasm counsel patients about the risks of adding any sedating medications, including over-the-counter products like diphenhydramine, without first consulting their healthcare provider. 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